Definition of NNRTI
1. Noun. An antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs.
Specialized synonyms: Delavirdine, Rescriptor, Nevirapine, Viramune
Group relationships: Drug Cocktail, Haart, Highly Active Antiretroviral Therapy
Generic synonyms: Reverse Transcriptase Inhibitor
Medical Definition of NNRTI
1. A member of a class of compounds, including delavirdine, loviride and nevirapine, that acts to directly combine with and block the action of HIV's reverse transcriptase (see). In contrast, nucleoside analogs block reverse transcriptase by capping the unfinished DNA chain that the enzyme is constructing. NNRTIs have suffered from HIV's ability to rapidly mutate and become resistant to their effects. (09 Oct 1997)
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Lexicographical Neighbors of NNRTI
NNRTI (current term)
Literary usage of NNRTI
Below you will find example usage of this term as found in modern and/or classical literature:
1. The Military Laws of the United States: Relating to the Army, Volunteers by United States, John F. Callan (1863)
"... of th« approbation of the Prc*iili<nt i« re-*nnrti»«l by thr I'1 Afrd. |x>4. of tb« ..."