Medical Definition of DNA probes

1. Species- or subspecies-specific DNA (including complementary DNA (DNA, complementary), conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridises with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32p and 125i and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections. (12 Dec 1998)

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Lexicographical Neighbors of DNA Probes

DNA modification methylases
DNA mutational analysis
DNA nucleotidylexotransferase
DNA nucleotidyltransferases
DNA photolyase
DNA polymerase
DNA polymerase II
DNA polymerase III
DNA polymerase beta
DNA polymerase i
DNA polymerisation
DNA polymorphism
DNA primase
DNA primers
DNA probe
DNA probes (current term)
DNA profiling
DNA puff
DNA rearrangement
DNA renaturation
DNA repair
DNA repair gene
DNA repair pathway
DNA replicase
DNA replication
DNA restriction-modification enzymes
DNA restriction enzymes
DNA reverse gyrase
DNA sequence
DNA sequence analysis

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