Medical Definition of DNA damage

1. Drug- or radiation-induced injuries in DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions which interfere with replication and transcription, as well as point mutations which disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair). If the damage is extensive, it can induce apoptosis. (12 Dec 1998)

Lexicographical Neighbors of DNA Damage

DNA-dependent ATPase-endonuclease
DNA-directed DNA polymerase
DNA-directed RNA polymerase
DNA-driven reaction
DNA-protein interaction
DNA (cytosine-5-)-methyltransferase
DNA N-glycosidase
DNA adducts
DNA alkyltransferase
DNA amplification
DNA annealing
DNA beta-glucosyltransferase
DNA binding protein
DNA chip
DNA cloning
DNA damage (current term)
DNA delta-helicase
DNA deoxyribophosphodiesterase
DNA diagnosis
DNA diagnostics
DNA duplex
DNA entry nuclease
DNA excision
DNA fingerprint
DNA fingerprinting
DNA footprinting
DNA fragmentation
DNA gap
DNA gene

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