Medical Definition of C type lectin
1.
| One of two classes of lectin produced by animal cells, the other being the S type.
The C type lectins require disulphide linked cysteines and Ca ions in order to bind to a specific carbohydrate (c.f. S type lectins). The carbohydrate recognition domain of C type lectins consists of about 130 amino acids which contains 18 invariant residues in a highly conserved pattern.
These invariant residues include cysteines which probably form disulphide bonds. So far, all identified C type lectins are extracellular proteins and include both Integral membrane proteins, such as the asialoglycoprotein receptor and soluble proteins.
(06 Aug 1998)
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Lexicographical Neighbors of C Type Lectin
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